Multiplex melanoma families are enriched for polygenic risk

Cancers, including cutaneous melanoma, can cluster in families. In addition to environmental etiological factors such as ultraviolet radiation, cutaneous melanoma has a strong genetic component. Genetic risks for cutaneous melanoma range from rare, high-penetrance mutations to common, low-penetrance...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Law, Matthew H, Aoude, Lauren G, Duffy, David L, Long, Georgina V, Johansson, Peter A, Pritchard, Antonia L, Khosrotehrani, Kiarash, Mann, Graham J, Montgomery, Grant W, Iles, Mark M, Cust, Anne E, Palmer, Jane M, Shannon, Kerwin F, Spillane, Andrew J, Stretch, Jonathan R, Thompson, John F, Saw, Robyn P M, Scolyer, Richard A, Martin, Nicholas G, Hayward, Nicholas K, MacGregor, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Association Studies Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7566496/
https://ncbi.nlm.nih.gov/pubmed/32716505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddaa156
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