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Highly cost-efficient genome-wide association studies using DNA pools and dense SNP arrays

Genome-wide association (GWA) studies to map genes for complex traits are powerful yet costly. DNA-pooling strategies have the potential to dramatically reduce the cost of GWA studies. Pooling using Affymetrix arrays has been proposed and used but the efficiency of these arrays has not been quantifi...

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Detalhes bibliográficos
Main Authors: Macgregor, Stuart, Zhao, Zhen Zhen, Henders, Anjali, Nicholas, Martin G., Montgomery, Grant W., Visscher, Peter M.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2346606/
https://ncbi.nlm.nih.gov/pubmed/18276640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm1060
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