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Tracking telomere fusions through crisis reveals conflict between DNA transcription and the DNA damage response
Identifying attributes that distinguish pre-malignant from senescent cells provides opportunities for targeted disease eradication and revival of anti-tumour immunity. We modelled a telomere-driven crisis in four human fibroblast lines, sampling at multiple time points to delineate genomic rearrange...
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| Publicado en: | NAR Cancer |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7787266/ https://ncbi.nlm.nih.gov/pubmed/33447828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/narcan/zcaa044 |
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