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Chromothripsis during telomere crisis is independent of NHEJ, and consistent with a replicative origin
Telomere erosion, dysfunction, and fusion can lead to a state of cellular crisis characterized by large-scale genome instability. We investigated the impact of a telomere-driven crisis on the structural integrity of the genome by undertaking whole-genome sequence analyses of clonal populations of ce...
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| Pubblicato in: | Genome Res |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6499312/ https://ncbi.nlm.nih.gov/pubmed/30872351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.240705.118 |
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