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An Additional Ca(2+) Binding Site Allosterically Controls TMEM16A Activation
Calcium (Ca(2+)) is the primary stimulus for transmembrane protein 16 (TMEM16) Ca(2+)-activated chloride channels and phospholipid scramblases, which regulate important physiological processes ranging from smooth muscle contraction to blood coagulation and tumor progression. Binding of intracellular...
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| Gepubliceerd in: | Cell Rep |
|---|---|
| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7786149/ https://ncbi.nlm.nih.gov/pubmed/33378669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108570 |
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