Evidence that polyphenols do not inhibit the phospholipid scramblase TMEM16F

TMEM16 Ca(2+)-activated phospholipid scramblases (CaPLSases) mediate rapid transmembrane phospholipid flip-flop and as such play essential roles in various physiological and pathological processes such as blood coagulation, skeletal development, viral infection, cell-cell fusion, and ataxia. Pharmac...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Le, Trieu, Le, Son C., Zhang, Yang, Liang, Pengfei, Yang, Huanghe
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2020
Subjects:
Accelerated Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7458812/
https://ncbi.nlm.nih.gov/pubmed/32709749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.AC120.014872
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