A carregar...

Granzyme B induces IRF-3 phosphorylation through a perforin-independent proteolysis-dependent signaling cascade without inducing cell death

Granzyme B (GrB) is an immune protease implicated in the pathogenesis of several human diseases. In the current model of GrB activity, perforin determines whether the downstream actions of GrB occur intracellularly or extracellularly, producing apoptotic cytotoxicity or non-apoptotic effects respect...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Gapud, Eric J., Trejo-Zambrano, Maria Isabel, Gomez-Banuelos, Eduardo, Tiniakou, Eleni, Antiochos, Brendan, Granville, David J., Andrade, Felipe, Casciola-Rosen, Livia, Rosen, Antony
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7785649/
https://ncbi.nlm.nih.gov/pubmed/33288544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000546
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!