The innate immune effector ISG12a promotes cancer immunity by suppressing the canonical Wnt/β-catenin signaling pathway

The ability to harness innate immunity is a promising solution for improving cancer immunotherapy. Interferon (IFN) induces expression of IFN-stimulated genes (ISGs) by activating the JAK-STAT signaling pathway to promote innate immunity and inhibit malignant tumor growth, but the functions and mech...

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Publicat a:Cell Mol Immunol
Autors principals: Deng, Rilin, Zuo, Chaohui, Li, Yongqi, Xue, Binbin, Xun, Zhen, Guo, Yanxia, Wang, Xiaohong, Xu, Yan, Tian, Renyun, Chen, Shengwen, Liu, Qian, Chen, Jinwen, Wang, Jingjing, Huang, Xiang, Li, Huiyi, Guo, Mengmeng, Wang, Xintao, Yang, Miaomiao, Wu, Zhihui, Wang, Jinfeng, Ma, Jiahuan, Hu, Jun, Li, Guangdi, Tang, Songqing, Tu, Zhengkun, Ji, Hongbin, Zhu, Haizhen
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7784998/
https://ncbi.nlm.nih.gov/pubmed/32963356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41423-020-00549-9
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