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Triplex-Forming Peptide Nucleic Acids with Extended Backbones
Peptide nucleic acid (PNA) forms a triple helix with double-stranded RNA (dsRNA) stabilized by a hydrogen-bonding zipper formed by PNA’s backbone amides (N-H) interacting with RNA phosphate oxygens. This hydrogen-bonding pattern is enabled by the matching ~5.7 Å spacing (typical for A-form dsRNA) be...
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| Publicado no: | Chembiochem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7783598/ https://ncbi.nlm.nih.gov/pubmed/32697857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000432 |
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