BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN

Deubiquitinase BAP1 is an important tumor suppressor in several malignancies, but its functions and critical substrates in prostate cancer (PCa) remain unclear. Here, we report that the mRNA and protein expression levels of BAP1 are downregulated in clinical PCa specimens. BAP1 can physically bind t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Oncol
Egile Nagusiak: Deng, Rong, Guo, Yanmin, Li, Lian, He, Jianfeng, Qiang, Zhe, Zhang, Hailong, Chen, Ran, Wang, Yanli, Zhao, Xian, Yu, Jianxiu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2020
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7782096/
https://ncbi.nlm.nih.gov/pubmed/33155366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12844
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