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Acetylation of AGO2 promotes cancer progression by increasing oncogenic miR-19b biogenesis
Argonaute2 (AGO2) is an effector of small RNA mediated gene silencing. Increasing evidence show that post-translational modifications of AGO2 can change miRNA activity at specific or global levels. Among the six mature miRNAs that are encoded by miR-17-92, miR-19b1 is the most powerful to exert the...
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| 出版年: | Oncogene |
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| 主要な著者: | , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group UK
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6372475/ https://ncbi.nlm.nih.gov/pubmed/30305728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41388-018-0530-7 |
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