SUMOylation of TARBP2 regulates miRNA/siRNA efficiency

Small RNA-induced gene silencing is essential for post-transcriptional regulation of gene expression; however, it remains unclear how miRNA/siRNA efficiency is regulated. Here we show that TARBP2 is SUMOylated at K52, which can be enhanced by its phosphorylation. This modification can stabilize TARB...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Chen, Cheng, Zhu, Changhong, Huang, Jian, Zhao, Xian, Deng, Rong, Zhang, Hailong, Dou, Jinzhuo, Chen, Qin, Xu, Ming, Yuan, Haihua, Wang, Yanli, Yu, Jianxiu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Pub. Group 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4673853/
https://ncbi.nlm.nih.gov/pubmed/26582366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9899
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller