SUMO1 modification of KHSRP regulates tumorigenesis by preventing the TL-G-Rich miRNA biogenesis

BACKGROUND: MicroRNAs (miRNAs) are important regulators involved in diverse physiological and pathological processes including cancer. SUMO (small ubiquitin-like modifier) is a reversible protein modifier. We recently found that SUMOylation of TARBP2 and DGCR8 is involved in the regulation of the mi...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Yuan, Haihua, Deng, Rong, Zhao, Xian, Chen, Ran, Hou, Guofang, Zhang, Hailong, Wang, Yanli, Xu, Ming, Jiang, Bin, Yu, Jianxiu
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637259/
https://ncbi.nlm.nih.gov/pubmed/29020972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0724-6
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