SUMOylation at K(707) of DGCR8 controls direct function of primary microRNA

DGCR8 (DiGeorge syndrome critical region gene 8) is essential for primary microRNA (pri-miRNA) processing in the cell nucleus. It specifically combines with Drosha, a nuclear RNase III enzyme, to form the Microprocessor complex (MC) that cleaves pri-miRNA to precursor miRNA (pre-miRNA), which is fur...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Zhu, Changhong, Chen, Cheng, Huang, Jian, Zhang, Hailong, Zhao, Xian, Deng, Rong, Dou, Jinzhuo, Jin, Hui, Chen, Ran, Xu, Ming, Chen, Qin, Wang, Yanli, Yu, Jianxiu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Molecular Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652762/
https://ncbi.nlm.nih.gov/pubmed/26202964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv741
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