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BAP1 suppresses prostate cancer progression by deubiquitinating and stabilizing PTEN
Deubiquitinase BAP1 is an important tumor suppressor in several malignancies, but its functions and critical substrates in prostate cancer (PCa) remain unclear. Here, we report that the mRNA and protein expression levels of BAP1 are downregulated in clinical PCa specimens. BAP1 can physically bind t...
Gespeichert in:
| Veröffentlicht in: | Mol Oncol |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7782096/ https://ncbi.nlm.nih.gov/pubmed/33155366 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12844 |
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