Pirfenidone facilitates immune infiltration and enhances the antitumor efficacy of PD-L1 blockade in mice

Idiopathic pulmonary fibrosis (IPF) patients have a high risk of developing lung cancer, with few treatment options available. Pirfenidone, an antifibrotic agent approved for the treatment of IPF, has been demonstrated to suppress the TGFβ signaling and modulate the expression of immune-related gene...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Qin, Wan, Zou, Jun, Huang, Yongbiao, Liu, Chaofan, Kang, Yalin, Han, Hu, Tang, Yang, Li, Long, Liu, Bo, Zhao, Weiheng, Yuan, Xianglin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7781712/
https://ncbi.nlm.nih.gov/pubmed/33457101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2020.1824631
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