Lung Myofibroblasts Promote Macrophage Profibrotic Activity through Lactate-induced Histone Lactylation

Augmented glycolysis due to metabolic reprogramming in lung myofibroblasts is critical to their profibrotic phenotype. The primary glycolysis byproduct, lactate, is also secreted into the extracellular milieu, together with which myofibroblasts and macrophages form a spatially restricted site usuall...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Cui, Huachun, Xie, Na, Banerjee, Sami, Ge, Jing, Jiang, Dingyuan, Dey, Tapan, Matthews, Qiana L., Liu, Rui-Ming, Liu, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2021
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780997/
https://ncbi.nlm.nih.gov/pubmed/33074715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2020-0360OC
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados