Metabolic characterization and RNA profiling reveal glycolytic dependence of profibrotic phenotype of alveolar macrophages in lung fibrosis

Metabolic reprogramming has been intrinsically linked to macrophage activation. Alveolar macrophages are known to play an important role in the pathogenesis of pulmonary fibrosis. However, systematic characterization of expression profile in these cells is still lacking. Furthermore, main metabolic...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Xie, Na, Cui, Huachun, Ge, Jing, Banerjee, Sami, Guo, Sijia, Dubey, Shubham, Abraham, Edward, Liu, Rui-Ming, Liu, Gang
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5792180/
https://ncbi.nlm.nih.gov/pubmed/28798256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00235.2017
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