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Inference for Multi Marker Adaptive Enrichment Trials

Identification of treatment selection biomarkers has become very important in cancer drug development. Adaptive enrichment designs have been developed for situations where a unique treatment selection biomarker is not apparent based on the mechanism of action of the drug, With such designs, the elig...

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Опубликовано в: :Stat Med
Главные авторы: Simon, Richard, Simon, Noah
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7780249/
https://ncbi.nlm.nih.gov/pubmed/28795420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.7422
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