Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion

BACKGROUND & AIMS: Macrophages are key regulators of inflammation and cancer promotion in the liver, and their recruitment and activation is linked to chemokine receptor signaling. However, the exact roles of the chemokine receptors CCR2 and CCR5 for macrophage functions in the liver is obscure....

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Mol Gastroenterol Hepatol
Auteurs principaux: Bartneck, Matthias, Koppe, Christiane, Fech, Viktor, Warzecha, Klaudia T., Kohlhepp, Marlene, Huss, Sebastian, Weiskirchen, Ralf, Trautwein, Christian, Luedde, Tom, Tacke, Frank
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Original Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779787/
https://ncbi.nlm.nih.gov/pubmed/32896623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.08.012
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