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Roles of CCR2 and CCR5 for Hepatic Macrophage Polarization in Mice With Liver Parenchymal Cell-Specific NEMO Deletion

BACKGROUND & AIMS: Macrophages are key regulators of inflammation and cancer promotion in the liver, and their recruitment and activation is linked to chemokine receptor signaling. However, the exact roles of the chemokine receptors CCR2 and CCR5 for macrophage functions in the liver is obscure....

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Bartneck, Matthias, Koppe, Christiane, Fech, Viktor, Warzecha, Klaudia T., Kohlhepp, Marlene, Huss, Sebastian, Weiskirchen, Ralf, Trautwein, Christian, Luedde, Tom, Tacke, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779787/
https://ncbi.nlm.nih.gov/pubmed/32896623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.08.012
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