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Loss of metabolic flexibility as a result of overexpression of pyruvate dehydrogenase kinases in muscle, liver and the immune system: Therapeutic targets in metabolic diseases

Good health depends on the maintenance of metabolic flexibility, which in turn is dependent on the maintenance of regulatory flexibility of a large number of regulatory enzymes, but especially the pyruvate dehydrogenase complex (PDC), because of its central role in carbohydrate metabolism. Flexibili...

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Detalhes bibliográficos
Publicado no:J Diabetes Investig
Main Authors: Jeon, Jae‐Han, Thoudam, Themis, Choi, Eun Jung, Kim, Min‐Ji, Harris, Robert A, Lee, In‐Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7779278/
https://ncbi.nlm.nih.gov/pubmed/32628351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jdi.13345
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