Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

During replication, hepatitis C virus (HCV) utilizes macromolecules produced by its host cell. This process requires host cellular metabolic reprogramming to favor elevated levels of aerobic glycolysis. Therefore, we evaluated whether pyruvate dehydrogenase kinase (PDK), a mitochondrial enzyme that...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Jung, Gwon-Soo, Jeon, Jae-Han, Choi, Yeon-Kyung, Jang, Se Young, Park, Soo Young, Kim, Sung-Woo, Byun, Jun-Kyu, Kim, Mi-Kyung, Lee, Sungwoo, Shin, Eui-Cheol, Lee, In-Kyu, Kang, Yu Na, Park, Keun-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965757/
https://ncbi.nlm.nih.gov/pubmed/27471054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30846
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