Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

During replication, hepatitis C virus (HCV) utilizes macromolecules produced by its host cell. This process requires host cellular metabolic reprogramming to favor elevated levels of aerobic glycolysis. Therefore, we evaluated whether pyruvate dehydrogenase kinase (PDK), a mitochondrial enzyme that...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Jung, Gwon-Soo, Jeon, Jae-Han, Choi, Yeon-Kyung, Jang, Se Young, Park, Soo Young, Kim, Sung-Woo, Byun, Jun-Kyu, Kim, Mi-Kyung, Lee, Sungwoo, Shin, Eui-Cheol, Lee, In-Kyu, Kang, Yu Na, Park, Keun-Gyu
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965757/
https://ncbi.nlm.nih.gov/pubmed/27471054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30846
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