Pyruvate dehydrogenase kinase regulates hepatitis C virus replication

During replication, hepatitis C virus (HCV) utilizes macromolecules produced by its host cell. This process requires host cellular metabolic reprogramming to favor elevated levels of aerobic glycolysis. Therefore, we evaluated whether pyruvate dehydrogenase kinase (PDK), a mitochondrial enzyme that...

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發表在:Sci Rep
Main Authors: Jung, Gwon-Soo, Jeon, Jae-Han, Choi, Yeon-Kyung, Jang, Se Young, Park, Soo Young, Kim, Sung-Woo, Byun, Jun-Kyu, Kim, Mi-Kyung, Lee, Sungwoo, Shin, Eui-Cheol, Lee, In-Kyu, Kang, Yu Na, Park, Keun-Gyu
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2016
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965757/
https://ncbi.nlm.nih.gov/pubmed/27471054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30846
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