Estrogen-related receptor γ is upregulated in liver cancer and its inhibition suppresses liver cancer cell proliferation via induction of p21 and p27

Orphan nuclear receptor estrogen-related receptor γ (ERRγ) regulates cell growth and tumorigenesis in various cancers. However, the clinical relevance of ERRγ to hepatocellular carcinoma (HCC) remains unclear. Here we examined the clinical significance of ERRγ in HCC and its potential as a therapeut...

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Pubblicato in:Exp Mol Med
Autori principali: Kim, Ji-Hyun, Choi, Yeon-Kyung, Byun, Jun-Kyu, Kim, Mi-Kyung, Kang, Yu Na, Kim, Seong Heon, Lee, Sungwoo, Jang, Byoung Kuk, Park, Keun-Gyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2016
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892874/
https://ncbi.nlm.nih.gov/pubmed/26940882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.115
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