Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2

Excessive vascular smooth muscle cell (VSMC) proliferation contributes to the development of atherosclerosis and restenosis. Furthermore, apoptosis of VSMCs accelerates plaque rupture in the atherosclerotic vessels. Therefore, a strategy that regulates both VSMC proliferation and apoptosis is essent...

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Publicado no:Exp Ther Med
Main Authors: Lee, Seunghyeong, Byun, Jun-Kyu, Park, Mihyang, Woo Kim, Sung, Lee, Sungwoo, Kim, Jung-Guk, Lee, In-Kyu, Choi, Yeon-Kyung, Park, Keun-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2020
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197251/
https://ncbi.nlm.nih.gov/pubmed/32373191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8638
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