Melatonin inhibits vascular smooth muscle cell proliferation and apoptosis through upregulation of Sestrin2

Excessive vascular smooth muscle cell (VSMC) proliferation contributes to the development of atherosclerosis and restenosis. Furthermore, apoptosis of VSMCs accelerates plaque rupture in the atherosclerotic vessels. Therefore, a strategy that regulates both VSMC proliferation and apoptosis is essent...

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Publicat a:Exp Ther Med
Autors principals: Lee, Seunghyeong, Byun, Jun-Kyu, Park, Mihyang, Woo Kim, Sung, Lee, Sungwoo, Kim, Jung-Guk, Lee, In-Kyu, Choi, Yeon-Kyung, Park, Keun-Gyu
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2020
Matèries:
Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7197251/
https://ncbi.nlm.nih.gov/pubmed/32373191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2020.8638
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