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Inhibitory Effect of a Glutamine Antagonist on Proliferation and Migration of VSMCs via Simultaneous Attenuation of Glycolysis and Oxidative Phosphorylation

Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of atherosclerosis and restenosis. Glycolysis and glutaminolysis are increased in rapidly proliferating VSMCs to support their increased energy requirements and biomass production. Thus, it is...

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Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Park, Hyeon Young, Kim, Mi-Jin, Lee, Seunghyeong, Jin, Jonghwa, Lee, Sungwoo, Kim, Jung-Guk, Choi, Yeon-Kyung, Park, Keun-Gyu
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198131/
https://ncbi.nlm.nih.gov/pubmed/34070527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115602
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