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Inhibitory Effect of a Glutamine Antagonist on Proliferation and Migration of VSMCs via Simultaneous Attenuation of Glycolysis and Oxidative Phosphorylation

Excessive proliferation and migration of vascular smooth muscle cells (VSMCs) contribute to the development of atherosclerosis and restenosis. Glycolysis and glutaminolysis are increased in rapidly proliferating VSMCs to support their increased energy requirements and biomass production. Thus, it is...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Park, Hyeon Young, Kim, Mi-Jin, Lee, Seunghyeong, Jin, Jonghwa, Lee, Sungwoo, Kim, Jung-Guk, Choi, Yeon-Kyung, Park, Keun-Gyu
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8198131/
https://ncbi.nlm.nih.gov/pubmed/34070527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22115602
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