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Estrogen-related receptor γ is upregulated in liver cancer and its inhibition suppresses liver cancer cell proliferation via induction of p21 and p27

Orphan nuclear receptor estrogen-related receptor γ (ERRγ) regulates cell growth and tumorigenesis in various cancers. However, the clinical relevance of ERRγ to hepatocellular carcinoma (HCC) remains unclear. Here we examined the clinical significance of ERRγ in HCC and its potential as a therapeut...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Kim, Ji-Hyun, Choi, Yeon-Kyung, Byun, Jun-Kyu, Kim, Mi-Kyung, Kang, Yu Na, Kim, Seong Heon, Lee, Sungwoo, Jang, Byoung Kuk, Park, Keun-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4892874/
https://ncbi.nlm.nih.gov/pubmed/26940882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2015.115
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