The pivotal role of pyruvate dehydrogenase kinases in metabolic flexibility

Metabolic flexibility is the capacity of a system to adjust fuel (primarily glucose and fatty acids) oxidation based on nutrient availability. The ability to alter substrate oxidation in response to nutritional state depends on the genetically influenced balance between oxidation and storage capacit...

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Main Authors: Zhang, Shuai, Hulver, Matthew W, McMillan, Ryan P, Cline, Mark A, Gilbert, Elizabeth R
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3925357/
https://ncbi.nlm.nih.gov/pubmed/24520982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-7075-11-10
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