Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis

Colorectal cancer (CRC) cells are traditionally considered unresponsive to TGFβ due to mutations in the receptors and/or downstream signaling molecules. TGFβ influences CRC cells only indirectly via stromal cells, such as cancer-associated fibroblasts. However, CRC cell ability to directly respond t...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Chiavarina, Barbara, Costanza, Brunella, Ronca, Roberto, Blomme, Arnaud, Rezzola, Sara, Chiodelli, Paola, Giguelay, Ambre, Belthier, Guillame, Doumont, Gilles, Van Simaeys, Gaetan, Lacroix, Simon, Yokobori, Takehiko, Erkhem-Ochir, Bilguun, Balaguer, Patrick, Cavailles, Vincent, Fabbrizio, Eric, Di Valentin, Emmanuel, Gofflot, Stephanie, Detry, Olivier, Jerusalem, Guy, Goldman, Serge, Delvenne, Philippe, Bellahcène, Akeila, Pannequin, Julie, Castronovo, Vincent, Turtoi, Andrei
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2021
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778592/
https://ncbi.nlm.nih.gov/pubmed/33408771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.51507
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