Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer

BACKGROUND: Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-β1 has been identified as a key driving force behind metastatic breast cancer, with promising therapeutic implications. METHODS AND F...

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Vydáno v:PLoS Med
Hlavní autoři: Maris, Pamela, Blomme, Arnaud, Palacios, Ana Perez, Costanza, Brunella, Bellahcène, Akeila, Bianchi, Elettra, Gofflot, Stephanie, Drion, Pierre, Trombino, Giovanna Elvi, Di Valentin, Emmanuel, Cusumano, Pino G., Maweja, Sylvie, Jerusalem, Guy, Delvenne, Philippe, Lifrange, Eric, Castronovo, Vincent, Turtoi, Andrei
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556693/
https://ncbi.nlm.nih.gov/pubmed/26327350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001871
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