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Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer

BACKGROUND: Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-β1 has been identified as a key driving force behind metastatic breast cancer, with promising therapeutic implications. METHODS AND F...

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Bibliografske podrobnosti
izdano v:PLoS Med
Main Authors: Maris, Pamela, Blomme, Arnaud, Palacios, Ana Perez, Costanza, Brunella, Bellahcène, Akeila, Bianchi, Elettra, Gofflot, Stephanie, Drion, Pierre, Trombino, Giovanna Elvi, Di Valentin, Emmanuel, Cusumano, Pino G., Maweja, Sylvie, Jerusalem, Guy, Delvenne, Philippe, Lifrange, Eric, Castronovo, Vincent, Turtoi, Andrei
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4556693/
https://ncbi.nlm.nih.gov/pubmed/26327350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001871
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