Extracellular vesicles derived from hypoxic glioma stem-like cells confer temozolomide resistance on glioblastoma by delivering miR-30b-3p

Rationale: Glioma stem-like cells (GSCs) contribute to temozolomide (TMZ) resistance in gliomas, although the mechanisms have not been delineated. Methods: In vitro functional experiments (colony formation assay, flow cytometric analysis, TUNEL assay) were used to assess the ability of extracellular...

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Publicat a:Theranostics
Autors principals: Yin, Jianxing, Ge, Xin, Shi, Zhumei, Yu, Chen, Lu, Chenfei, Wei, Yutian, Zeng, Ailiang, Wang, Xiefeng, Yan, Wei, Zhang, Junxia, You, Yongping
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2021
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778586/
https://ncbi.nlm.nih.gov/pubmed/33408780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.47057
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