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Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

BACKGROUND: Acquired drug resistance is a constraining factor in clinical treatment of glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire therapeutic resistance remain poorly understood. Here, we aim to investigate whether temozolomide (TMZ) resistance of chemoresponsive G...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Zhang, Zhuoran, Yin, Jianxing, Lu, Chenfei, Wei, Yutian, Zeng, Ailiang, You, Yongping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469146/
https://ncbi.nlm.nih.gov/pubmed/30992025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1139-6
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