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Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

BACKGROUND: Acquired drug resistance is a constraining factor in clinical treatment of glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire therapeutic resistance remain poorly understood. Here, we aim to investigate whether temozolomide (TMZ) resistance of chemoresponsive G...

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Podrobná bibliografie
Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Zhang, Zhuoran, Yin, Jianxing, Lu, Chenfei, Wei, Yutian, Zeng, Ailiang, You, Yongping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469146/
https://ncbi.nlm.nih.gov/pubmed/30992025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1139-6
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