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Exosomal transfer of long non-coding RNA SBF2-AS1 enhances chemoresistance to temozolomide in glioblastoma

BACKGROUND: Acquired drug resistance is a constraining factor in clinical treatment of glioblastoma (GBM). However, the mechanisms of chemoresponsive tumors acquire therapeutic resistance remain poorly understood. Here, we aim to investigate whether temozolomide (TMZ) resistance of chemoresponsive G...

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Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Zhang, Zhuoran, Yin, Jianxing, Lu, Chenfei, Wei, Yutian, Zeng, Ailiang, You, Yongping
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6469146/
https://ncbi.nlm.nih.gov/pubmed/30992025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-019-1139-6
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