EIF4A3-induced circular RNA ASAP1 promotes tumorigenesis and temozolomide resistance of glioblastoma via NRAS/MEK1/ERK1–2 signaling

BACKGROUND: Acquired chemoresistance is a major challenge in the clinical treatment of glioblastoma (GBM). Circular RNAs have been verified to play a role in tumor chemoresistance. However, the underlying mechanisms remain unclear. The aim of this study was to elucidate the potential role and molecu...

Full description

Saved in:
Bibliographic Details
Published in:Neuro Oncol
Main Authors: Wei, Yutian, Lu, Chenfei, Zhou, Peng, Zhao, Lin, Lyu, Xiao, Yin, Jianxing, Shi, ZhuMei, You, Yongping
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Basic and Translational Investigations
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8041353/
https://ncbi.nlm.nih.gov/pubmed/32926734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa214
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items