DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma

BACKGROUND: Accumulating evidence shows that long noncoding RNAs (lncRNAs) are important regulator molecules involved in diverse biological processes. Acquired drug resistance is a major challenge in the clinical treatment of glioblastoma (GBM), and lncRNAs have been shown to play a role in chemothe...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Main Authors: Lu, Chenfei, Wei, Yutian, Wang, Xiefeng, Zhang, Zhuoran, Yin, Jianxing, Li, Wentao, Chen, Lijiu, Lyu, Xiao, Shi, Zhumei, Yan, Wei, You, Yongping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7011291/
https://ncbi.nlm.nih.gov/pubmed/32039732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-020-1137-5
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