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GTP metabolic reprogramming by IMPDH2: unlocking cancer cells’ fuelling mechanism
Growing cells increase multiple biosynthetic processes in response to the high metabolic demands needed to sustain proliferation. The even higher metabolic requirements in the setting of cancer provoke proportionately greater biosynthesis. Underappreciated key aspects of this increased metabolic dem...
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| Publicado no: | J Biochem |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7778356/ https://ncbi.nlm.nih.gov/pubmed/32702086 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvaa085 |
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