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Mechanisms of Metabolic Reprogramming in Cancer Cells Supporting Enhanced Growth and Proliferation

Cancer cells alter metabolic processes to sustain their characteristic uncontrolled growth and proliferation. These metabolic alterations include (1) a shift from oxidative phosphorylation to aerobic glycolysis to support the increased need for ATP, (2) increased glutaminolysis for NADPH regeneratio...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Schiliro, Chelsea, Firestein, Bonnie L.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8146072/
https://ncbi.nlm.nih.gov/pubmed/33946927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells10051056
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