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Molecular mechanisms of metabolic reprogramming in proliferating cells: implications for T-cell-mediated immunity
To engage in proliferation, cells need to increase their biomass and replicate their genome. This process presents a substantial bioenergetic challenge: proliferating cells must increase ATP production and acquire or synthesize raw materials, including lipids, proteins and nucleic acids. To do so, p...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2012
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401974/ https://ncbi.nlm.nih.gov/pubmed/22384794 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03583.x |
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