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GTP metabolic reprogramming by IMPDH2: unlocking cancer cells’ fuelling mechanism

Growing cells increase multiple biosynthetic processes in response to the high metabolic demands needed to sustain proliferation. The even higher metabolic requirements in the setting of cancer provoke proportionately greater biosynthesis. Underappreciated key aspects of this increased metabolic dem...

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Dades bibliogràfiques
Publicat a:J Biochem
Autors principals: Kofuji, Satoshi, Sasaki, Atsuo T
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7778356/
https://ncbi.nlm.nih.gov/pubmed/32702086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jb/mvaa085
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