168. Efficacy of the Novel gwt1 Inhibitor APX2039 in a Rabbit Model of cryptococcus Meningitis

BACKGROUND: Cryptococcal meningitis (CM), caused primarily by Cryptococcus neoformans, is uniformly fatal if not treated. Treatment options are limited especially in resource-poor geographical regions, and mortality rates remain high despite current therapies. New oral treatment options are needed t...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Open Forum Infect Dis
Autori principali: Shaw, Karen J, Giamberardino, Charles D, Soltow, Quinlyn A, Tenor, Jennifer, Toffaletti, Dena, Boua, Jane-Valeriane, Marius, Choiselle, Palmucci, Julia R, Perfect, John R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2020
Soggetti:
Poster Abstracts
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777792/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofaa439.478
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