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Fungal Cytological Profiling of Candida albicans Exposed to Diverse Antifungal Agents Including the Novel Gwt1 inhibitor APX001A

BACKGROUND: Bacterial cytological profiling accelerates drug discovery efforts by determining the mechanism of action (MOA) of newly developed antibacterial agents. Our goal was to adapt this technology to the identification and study of the MOA of antifungal compounds. Here we explore the utility o...

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Detalhes bibliográficos
Publicado no:Open Forum Infect Dis
Main Authors: Sharp, Marc, Soltow, Quinlyn, Shaw, Karen Joy, Pogliano, Joseph
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631029/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1218
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