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Fungal Cytological Profiling of Candida albicans Exposed to Diverse Antifungal Agents Including the Novel Gwt1 inhibitor APX001A

BACKGROUND: Bacterial cytological profiling accelerates drug discovery efforts by determining the mechanism of action (MOA) of newly developed antibacterial agents. Our goal was to adapt this technology to the identification and study of the MOA of antifungal compounds. Here we explore the utility o...

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Publicat a:Open Forum Infect Dis
Autors principals: Sharp, Marc, Soltow, Quinlyn, Shaw, Karen Joy, Pogliano, Joseph
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5631029/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofx163.1218
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