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Quinine copolymer reporters promote efficient intracellular DNA delivery and illuminate a protein-induced unpackaging mechanism

Polymeric vehicles that efficiently package and controllably release nucleic acids enable the development of safer and more efficacious strategies in genetic and polynucleotide therapies. Developing delivery platforms that endogenously monitor the molecular interactions, which facilitate binding and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Van Bruggen, Craig, Punihaole, David, Keith, Allison R., Schmitz, Andrew J., Tolar, Jakub, Frontiera, Renee R., Reineke, Theresa M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7777095/
https://ncbi.nlm.nih.gov/pubmed/33318196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2016860117
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