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Intracellular Trafficking of Polyamidoamine – Polyethylene Glycol Block Copolymers in DNA Delivery

The delivery of nucleic acids has the potential to revolutionize medicine by allowing previously untreatable diseases to be clinically addressed. Viral delivery systems have shown immunogenicity and toxicity dangers, but synthetic vectors have lagged in transfection efficiency. Previously, we have d...

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Hlavní autoři: Bonner, Daniel K., Leung, Cheuk, Chen-Liang, Jane, Chingozha, Loice, Langer, Robert, Hammond, Paula T
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218102/
https://ncbi.nlm.nih.gov/pubmed/21761838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc200059v
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