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Multifunctional triblock copolymers for intracellular messenger RNA delivery

Messenger RNA (mRNA) is a promising alternative to plasmid DNA (pDNA) for gene vaccination applications, but safe and effective delivery systems are rare. Reversible addition-fragmentation chain transfer (RAFT) polymerization was employed to synthesize a series of triblock copolymers designed to enh...

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Detalhes bibliográficos
Main Authors: Cheng, C., Convertine, A.J., Stayton, P.S., Bryers, J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412061/
https://ncbi.nlm.nih.gov/pubmed/22784603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2012.06.020
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