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New Insights into Quinine–DNA Binding Using Raman Spectroscopy and Molecular Dynamics Simulations
Quinine’s ability to bind DNA and potentially inhibit transcription and translation has been examined as a mode of action for its antimalarial activity. UV absorption and fluorescence-based studies have lacked the chemical specificity to develop an unambiguous molecular-level picture of the binding...
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| Publié dans: | J Phys Chem B |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6425490/ https://ncbi.nlm.nih.gov/pubmed/30336027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.8b05795 |
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