SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

The spike aspartic acid–614 to glycine (D614G) substitution is prevalent in global severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) strains, but its effects on viral pathogenesis and transmissibility remain unclear. We engineered a SARS-CoV-2 variant containing this substitution. The var...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Science
Main Authors: Hou, Yixuan J., Chiba, Shiho, Halfmann, Peter, Ehre, Camille, Kuroda, Makoto, Dinnon, Kenneth H., Leist, Sarah R., Schäfer, Alexandra, Nakajima, Noriko, Takahashi, Kenta, Lee, Rhianna E., Mascenik, Teresa M., Graham, Rachel, Edwards, Caitlin E., Tse, Longping V., Okuda, Kenichi, Markmann, Alena J., Bartelt, Luther, de Silva, Aravinda, Margolis, David M., Boucher, Richard C., Randell, Scott H., Suzuki, Tadaki, Gralinski, Lisa E., Kawaoka, Yoshihiro, Baric, Ralph S.
Format: Artigo
Sprog:Inglês
Udgivet: American Association for the Advancement of Science 2020
Fag:
Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7775736/
https://ncbi.nlm.nih.gov/pubmed/33184236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.abe8499
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker